R100 terminates at 69th street, right? From there you can get on the Market-Frankford subway line, which goes all the way across Philly, east-west-wise, and connects up with other trolley/subway/buses at various points. (I know this from riding the M-F line every day to work and not having anything to do but stare at the SEPTA map.)

I have never been out that far on the M-F line, so I don't know if the neighborhood is skanky or not....